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MOIS Series --- HTP / HT / HTX

MOIS Series

Introduction

The MOIS Series (HTP / HT / HTX) delivers high-performance in vivo imaging for small animal studies across oncology, immunology, pharmacology, and stem cell research.
With a back-illuminated CCD (≥90% quantum efficiency) and cooling capacity up to -90°C, MOIS ensures exceptional sensitivity for low-light applications. The fluorescence module features up to 26 narrowband filters and advanced spectral unmixing algorithms, improving multi-color accuracy and quantification.
Supporting a range of imaging fields from 2.5 × 2.5 cm to 25 × 25 cm, the system adapts to localized or whole-body needs. Built-in correction technologies—including bias, flat-field, background suppression, and cosmic ray removal—ensure consistent, reproducible results, ideal for high-standard in vivo research workflows.

Advantages

  • Ultra-High Sensitivity
  • Broad Spectral Compatibility
  • Reliable Multimodal Imaging
  • Quantitative Accuracy
  • Scalable Field of View
  • Data Consistency

Applications

  • Cancer
  • Drug Development
  • Immunity & Stem Cells
  • Developmental Biology
  • Neuroscience
  • Genetics & Molecular Biology

Features

  • Equipped with a back-illuminated, -90°C depth-cooled CCD camera to effectively reduce background noise.
  • Features a quantum efficiency of > 90%, with special coating processing on the chip to ensure high sensitivity in the 500-700nm range.
  • F/Stop≤ 0.95.Lens collects more photons per unit time, capturing finer details and less noise.
  • Covers a wide wavelength range of 400-900 nm, suitable for variouscommonly used dyes and probes in scientific research scenarios.
  • Includes standard equipment with 19 excitation filters and 7 emission narrow band filters, ensuring a pure signal to avoid color crosstalk and provide realistic data.
  • The calibrated light source meets NIST standards for absolutebioluminescence quantification, ensuring consistent results across imaging parameters.
  • Excitation light intensity uniformity guarantees consistent strength across various fields of view, enhancing the reliability of fluorescence data collection.
  • Field of view (FOV) ≥ 25cm × 25cm, enables simultaneous monitoring of at least 5 animals.
  • Equipped with a 5-channel anesthesia tray and active scavenging masks to prevent anesthetic gas leakage.

Specifications

ModuleParametersMOIS HTPMOIS HTMOIS HTX
Imaging ModulesFluorescence Imaging Module√√√
Bioluminescence Imaging Module√√√
Spectral High-Resolution Imaging√√√
X-Ray Module××√
Upconversion Fluorescence Imaging (UCFI) ModuleExpandable & Upgradeable
DetectorCamera TypeBack-illuminated sensor, Scientific-grade CCD
Operating Temperature-70℃-90℃-90℃
Pixel Count1024×1024
Aperture (F-Stop)≤ 0.95
Minimum FOV (Field of View)2.5cm × 2.5cm(optional)
Maximum FOV25cm × 25cm
Quantum Efficiency≥90%(500–700nm)
Laser SystemBroadband Light Source150W Halogen-tungsten broadband
Guide LaserReal-time FOV center display for positioning
FiltersExcitation Filters19
Emission Filters7
SoftwareReal-time Acquisition SystemSupports real-time image acquisition with light prompts, time series module, communication connection, and bioluminescence/fluorescence multi-mode imaging switching. Synchronous acquisition module supported.
Offline Analysis WorkstationSupport image analysis, time spectrum analysis module, need to be authorized by molecular software quantitative module
Environmental ControlMulti-Animal Imaging Chamber5 channels
Temperature ModuleTemperature control range: 20-40 ℃, accuracy: ±0.1℃
Anesthesia SystemAnesthesia gas control:iso
concentration: 0.5%-5% adjustable

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