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Biological Signals Recording Catheter System
Current electrophysiology catheter systems designed for human and large animal studies are not suitable for small animal models due to their size, sensitivity, and precision requirements. Small animals, such as rodents, are essential in preclinical research for understanding cardiac electrophysiology and developing treatments for various cardiac conditions. However, the lack of appropriately scaled and sensitive catheter systems for small animals limits the ability to conduct accurate and reliable electrophysiological studies, hindering advancements in cardiac research and therapeutic development. The Key X Sciences EP catheter system is an excellent product that our clients have validated to solve this problem. The Key X Sciences EP catheter system is specifically designed for intracardiac or intraesophageal electrophysiology experiments in rodents and large animals. It allows for precise monitoring of electrical signals from the heart or esophagus, enabling researchers to investigate cardiac arrhythmias and other electrophysiological phenomena in small animal models.
Products
Product Descriptions
Intracardiac EP Catheter
The Intracardiac EP catheter is used to determine electrical properties of the atrium and ventricle for various small animals. It is commonly employed in studies involving experimental animals such as mice to investigate cardiac arrhythmias by applying pacing and recording operations within the heart. This allows for the determination of the electrical characteristics of the atria and ventricles, facilitating standard electrophysiological research in rodents and other small animals. Programmed electrical stimulation is also delivered through the catheter for induction of arrhythmia, such as atrial fibrillation.
- Monitor intracardiac electrical signals
- Capable of simultaneously collecting ECG signals from multiple locations.
- Can simultaneously collect signals and deliver stimulation.
- The number, size and spacing of electrodes can be customized. Size 1.2 F intracardiac catheter is recommended for mice. Size 2.4 F intracardiac catheter is recommended for rats.
- Compatible with a variety of bioelectric amplifiers, stimulators, and data collectors.
Transesophageal EP Catheter
Capable of simultaneously collecting ECG signals from multiple locations. Can simultaneously collect signals and deliver stimulation. The number, size and spacing of electrodes can be customized. Compatible with a variety of bioelectric amplifiers, stimulators, and data collectors.
- Mouse esophagus: 2.4F
- Rat esophagus: 4.0F
Intracardiac Pressure Catheter
The Intracardiac Pressure Catheter for rodents offers precise and reliable measurement of intracardiac pressures, providing essential data for cardiovascular research. Engineered for use in small animals, this catheter features a high-fidelity sensor that ensures accurate readings of pressure changes within the heart chambers. Its design minimizes trauma to the animal, enhancing the reliability of experimental outcomes. This catheter is an invaluable tool for researchers aiming to understand cardiac mechanics, evaluate disease models, and test new treatments in the preclinical phase.
Fiber Optic Pressure Catheter
The Fiber Optic Pressure Catheter offers cutting-edge pressure measurement capabilities with unparalleled accuracy and sensitivity. Utilizing advanced fiber optic technology, this catheter is designed to deliver real-time, high-resolution pressure data from within the cardiovascular system. Its compact and minimally invasive design is suitable for both clinical applications and preclinical research involving small animals such as rodents. The catheter’s robustness and reliability make it an indispensable tool for researchers and clinicians aiming to gain deeper insights into cardiovascular function and disease.
Catheter Adaptive Box
The electrode switch box selects the required electrodes through knob switches, eliminating the need for plugging and unplugging adapter cables. The electrode switch box connects to the bioelectric amplifier or stimulator via 2mm pin-type adapter cables, making it convenient for conducting various aspects of cardiac electrophysiology research, including cardiac pacing and electrical signal recording applications, using electrophysiological catheters.
Made of aluminum alloy material to isolate signal interference, the electrode adapter box independently controls each adapter cable to prevent signal interference. For each adapter cable, you can use the rotary switch to select the electrode signal that needs to be connected, eliminating the need to unplug and switch the adapter cable.
Support eight electrode wires. Multiple grounding sockets are reserved.
Dual-Channel Programmable Electric Stimulator
The dual-channel programmable electrical stimulator is a fully digital, software-controlled stimulator capable of delivering constant voltage and constant current output. When used with a high-voltage isolator, it can achieve voltage outputs of up to 100V. This device can be used for stimulating tissues such as nerves and muscles ex vivo, as well as for in vivo experiments, with enhanced functionality specifically tailored for cardiovascular research applications.
The dual-channel computer-controlled electrical stimulator connects to a computer via a type-C interface and utilizes computer software to configure stimulation programs. Additionally, the instrument features external triggering and TTL output interfaces, enhancing the versatility and functionality of the device’s operation.
Product features:
- Constant voltage and constant current outputs are optional.
- Dual-channel stimulation output, with additional TTL signal output that can be independently controlled and programmed.
- The standard version provides a maximum constant current output of 20 mA and a constant voltage output of 10 V. By incorporating an optional high-voltage isolator, the maximum constant voltage output increases to 100 V, while the maximum constant current increases to 100 mA.
- Multiple stimulation waveforms available
- Built-in impedance detection functionality
- Support synchronous output of the output channel and TTL.
- The high-voltage isolator is equipped with an external independent power supply to ensure high signal quality.
- Support programmed S1S1 and S1Sx output, and support fully customized wave output.
- Wide frequency range ( 0.1 Hz-1000 Hz), wide pulse (> 0.2 ms)，with charge compensation function.
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